Restless legs syndrome (RLS) causes an uncontrollable urge to move the legs due to uncomfortable sensations, usually in the evening while sitting, lying down, or sleeping. In this study, 45 people with RLS continued taking standard management with or without 150 mg of Pycnogenol® per day.
After four weeks, Pycnogenol was at least three times as effective as standard management alone in reducing symptoms, including pulling, creeping, crawling, throbbing, aching, itching, swelling, electric shocks, and sleep problems. Those taking Pycnogenol were also less likely to need analgesics for pain and had lower levels of oxidative stress compared to those taking standard management alone.
Reference: Panminerva Medica; 2022, Vol. 64, No. 2, 253-8